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Age and chronodisruption in mouse heart: Effect of the NLRP3 inflammasome and melatonin therapy

A review of comparative studies

10.1164/rccm.200205-446OC Am J Respir Crit Care Med

In Study 2, adjudicated serious adverse events of atrial fibrillation in the zoledronic acid treatment group occurred in 1.0% of patients (11 out of 1054) compared to 1.2% (13 out of 1057) in the placebo group demonstrating no difference between treatment groups